Gao Lab

Publications

(* corresponding author)

KSHV and KSHV-related original works:

  1. Lee MS, Jones T, Song DY, Jang JH, Jung JU, Gao S-J*. Exploitation of complement system by oncogenic Kaposi’s sarcoma-associated herpesvirus for cell survival and persistent infection. PLoS Pathogens, 10(9): e1004412. doi:10.1371/journal.ppat.1004412.

    2. 2-Complement activation
  2. Xue M, Yao SH, Hu MM, Li W, Hao TT, Zhou F, Zhu XF, Qin D, Yan Q, Zhu JH, Gao S-J, Lu C. HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway. Nucleic Acid Research, 2014, 42, 9862-9879.
  3. Brulois K, Toth Z, Wong LY, Feng PH, Gao S-J, Ensser A, Jung JU. KSHV K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication. Journal of Virology, 2014, 88, 9335-9349.
  4. Liang DG, Hu H, Li SS, Dong JZ, Wang X, Wang YH, He L, He ZH, Gao Y, Gao S-J*, and Lan K*. Oncogenic herpesvirus KSHV hijacks BMP-smad1-Id signaling to promote tumorigenesis. PLoS Pathogens, 10(7): e1004253. doi:10.1371/journal.ppat.1004253.
  5. Li QH‡, He ML‡, Zhou FC, Ye FC and Gao S-J*. Activation of Kaposi’s sarcoma-associated herpesvirus by inhibitors of class III histone deacetylases: identification of SIRT1 as a regulator of KSHV life cycle. Journal of Virology, 2014, 88, 6355-6367 (‡Equal contribution).
  6. Yan Q, Xinting Ma, Cao X, Feng NH, Wang ZD, Li JM, Qin D, Zeng Y, Zhu JZ, Gao S-J, Lu C. Inhibition of Kaposi’s sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258. Journal of Virology, 2014, 88, 4987-5000.
  7. Jones T, Ramos da Silva S, Bedolla R, Ye FC, Zhou FC and Gao S-J*. vCyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact-inhibition. Cell Cycle, 2014, 13, 845-858.
  8. Bai ZQ, Huang YF, Li W, Zhu Y, Jung JU, Lu C*, Gao S-J*. Genome-wide mapping and screening of 3’UTRs identify bicistronic and polycistronic viral transcripts as common targets of KSHV microRNAs. Journal of Virology, 2014, 88, 377-392.

  9. Moody R, Zhu Y, Huang YF*, Cui XD, Jones T, Bedolla R, Lei XF, Bai ZQ, Gao S-J*. KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways. PLoS Pathogens, 2013, 9(12): e1003857. doi:10.1371/journal.ppat. 1003857. (Recommended Article by the Faculty of 1000 Prime, evaluated by Howard Young and Miranda L. Hanson on January. 20, 2014).

    10. 16-miRNA transformaiton
  10. Wong LY, Brulois K, Toth Z, Inn KS, Lee SH, O’Brien K, Lee HR, Gao S-J, Cesarman E, Ensser A, and Jung JU. KSHV K4.2 immediate early gene product regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1. Journal of Virology, 2013, 87, 12069-12079.
  11. Ye FC*, Zhou FC, Nithianantham S, Chandran B, Yu XL, Weinberg A and Gao S-J*. Kaposi’s sarcoma-associated herpesvirus induces rapid release of angiopoietin-2 from endothelial cells. Journal of Virology, 2013, 87, 6326-6335.
  12. Zhou F, Xue M, Qin D, Zhu XF, Wang C, Zhu JZ, Hao TT, Cheng L, Chen XY, Bai ZQ, Feng NH, Gao S-J, Lu C. HIV-1 Tat promotes Kaposi’s sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathway. PLoS One, 2013, 8(1): e53145. doi:10.1371/journal.pone.0053145.
  13. Lei XF‡, Zhu Y‡. Jones T, Ye FC, Bai ZQ, Huang YF and Gao S-J*. A KSHV microRNA and its variants target TGF-β pathway to promote cell survival. Journal of Virology, 2012, 86, 11698-11711 (‡Equal contribution).
  14. Brulois K, Chang H, Lee A, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung JJ, Ganem D, Oh TK, Kim JF, Gao S-J and Jung JU. Construction and manipulation of a new Kaposi’s sarcoma-associated herpesvirus bacterial artificial chromosome clone Journal of Virology, 2012, 86, 9708-9720.
  15. He ML*, Zhang W, Bakken T, Schutten M, Toth Z, Jung JU, Gill P, Cannon M*, Gao S-J*. Cancer angiogenesis-induced by Kaposi’s sarcoma-associated herpesvirus is mediated by EZH2. Cancer Research, 2012, 72, 3582-3592.
  16. Greene W‡, Zhang W‡, He ML, Witt C, Ye FC and Gao S-J*. The ubiquitin/proteasome system regulates Kaposi’s sarcoma-associated herpesvirus entry into endothelial cells. PLoS Pathogens, 2012, 8(5): e1002703. doi:10.1371/journal.ppat.1002703 (‡Equal contribution).
  17. Ye FC*, Ali AAL, Xie JP, Weinberg A, Gao S-J*. Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi’s sarcoma tumor cells. Cell Cycle, 2012,11, 1393-1399.
  18. Jones T‡, Ye FC‡, Bedolla RG‡, Huang YF, Meng J, Qian LW, Pan HY, Zhou FC, Moody R, Wagner, B, Arar M and Gao S-J*. Direct efficient cellular transformation of primary rat metanephric mesenchymal cells by KSHV. Journal of Clinical Investigation, 2012, 122, 1076-1081 (‡Equal contribution). (Recommended Article by the Faculty of 1000 Biology, evaluated by Patrick S. Moore and Lindsay Dresang on Feb. 20, 2012).
  19. Bai ZQ, Zhou FC, Lei XF, Ma XT, Lu C, Gao S-J*. A cluster of transcripts encoded by KSHV ORF30-33 gene locus. Virus and Genes, 2012, 44, 225-236.
  20. Zhang W, Greene W, Gao S-J*. Microtubule- and dynein-dependent nuclear trafficking of rhesus rhadinovirus in rhesus fibroblasts. Journal of Virology, 2012, 86, 599-604.
  21. Fu BS, Xia F, Li BL, Ouyang XX, Gao S-J, Yang RG and Wang LD. Gender difference of Kaposi’s sarcoma-associated herpesvirus infection in population with schistosomiasis in rural China. Japanese Journal of Infectious Diseases. 2012, 65, 350-353.

  22. Ye FC, Zhou FC, Bedolla, RG, Jones T, Lei XF, Kang T, Guadalupe M, and Gao S-J*. Reactive oxygen species hydrogen peroxide induces Kaposi’s sarcoma-associated herpesvirus reactivation from latency. PLoS Pathogens, 2011, 7(5): e1002054.

    23. 3-ROS-NAC
  23. Guadalupe M, Pollock BH, Westbrook S, Redding S, Bullock D, Anstead G, Agan BK, Marconi VC, Barbieri S, Sankar V, Rebeles J, Flahive Y, Schoolfield J, Wang LD, Lei XF, Dow D, Yeh CK, Dang H, Infante AJ, Gao S-J*. Risk factors for prevalence and lytic antibody titer of Kaposi’s sarcoma-associated herpesvirus in HIV-infected subjects under antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 2011, 56, 83-90.
  24. Zhang W, Zhou FC, Greene W, Gao S-J*. Rhesus rhadinovirus infection of rhesus fibroblasts occurs through clathrin-mediated endocytosis. Journal of Virology, 2010, 84, 11709-11717.
  25. Zhou FC, Li QH, Wong SW, and Gao S-J*. Terminal repeat-mediated auto-excision of bacteria artificial chromosome: a novel approach for generating traceless genetic mutants of herpesviruses. Journal of Virology, 2010, 84, 2871-2880 (Featured in the journal’s “Spotlight” selected by the Editors, Journal of Virology, 84, 2635)
  26. Lei XF, Bai ZQ, Ye FC, Xie JP, Kim CG, Huang YF and Gao S-J*. Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA. Nature Cell Biology, 2010, 12, 193-199. (Recommended Article by the Faculty of 1000 Biology, evaluated by Blossom Damania on Jan. 21, 2010) (Selected as “Research Highlight” in Nature Reviews Microbiology, 2010, 8, 158-159) (Selected article in FOCUS on NF-κB Signaling by Cell Research, 2011).
  27. Marcos-Villar L, Fernando Lopitz-Otsoa F, Gallego P, Muñoz-Fontela C, González-Santamaría J, Campagna M, Gao SJ, Rodriguez M and Rivas C. KSHV protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of Survivin gene. Journal of Virology, 2009, 83, 8849-8858.
  28. Greene W and Gao S-J*. Actin dynamics regulate clathrin-mediated endocytosis during Kaposi’s sarcoma-associated herpesvirus entry into endothelial cells. PLoS Pathogens, 2009, 5(7): e1000512.
  29. Fu BS, Sun F, Li BL, Yang L, Zeng Y, Sun XL, Xu FH, Rayner S, Guadalupe M, Gao S-J* and Wang L-D*. Kaposi’s sarcoma-associated herpesvirus seroprevalence, risk factors and genotypes in Xinjiang, China. Journal of Medical Virology, 2009, 23, 1422-1431.
  30. Chen JG, Ye FC, Xie JP, Kuhne, K and Gao S-J*. Genome-wide identification of binding sites for Kaposi’s sarcoma-associated herpesvirus lytic switch protein, RTA. Virology, 2009, 386, 290-302.
  31. Zhou FC, Li QH, Gao S-J*. A sequence-independent in vitro transposon-based strategy for efficient cloning of genomes of large DNA viruses as bacterial artificial chromosomes. Nucleic Acid Research, 2009, 37:e2.
  32. Lee JS, Li QL, Lee SH, Lee HR, Chang HS, Zhou FC, Gao S-J, Liang CY, and Jung JU. FLIP-mediated autophagy in cell death control. Nature Cell Biology, 2009, 11, 1355-1362. (Recommended Article by the Faculty of 1000 Biology, evaluated by Robert Abraham on Nov. 6, 2009).

  33. Qian LW, Greene W, Ye FC and Gao S-J*. Kaposi’s sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin. Journal of Virology, 2008, 82, 11902-12.

    34. 13-Adherens junction
  34. Li QH, Zhou FC, Ye FC, Gao S-J*. Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program. Virology, 2008, 379, 234-244.
  35. Ye FC, Zhou FC, Xie JP, Kang T, Greene W, Kuhne K, Lei XF, Li QH, Gao S-J*. Kaposi’s sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-κB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency. Journal of Virology, 2008, 82, 4235-4249.
  36. Xie JP, Ajibade AO, Ye FC, Kuhne K and Gao S-J*. MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways are essential for the reactivation of Kaposi’s sarcoma-associated herpesvirus from latency. Virology, 2008, 371, 139-154.
  37. Muñoz-Fontela C, Villar LM, Hernandez F, Gallego P, Rodriguez E, Arroyo J, Gao S-J, Avila J, Rivas M. Induction of paclitaxel resistance by the KSHV latent protein LANA2. Journal of Virology, 2008, 82, 1518-1525.
  38. Cloutier N, Eyll OV, Lefort S, Janelle M-E, Gao S-J, Flamand L. Increased tumorigenicity of cells carrying recombinant human herpesvirus 8. Archives of Virology. 2008, 153, 93-103.
  39. Qian LW, Xie JP, Ye FC and Gao S-J*. Kaposi’s sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases. Journal of Virology, 2007, 81, 7001-7010.
  40. Nun T, Kroll DJ, Oberlies NH, Soejarto DD, Case R, Piskaut P, Matainaho T, Hilscher C, Wang L, Dittmer DP, Gao S-J and Damania B. Development of a fluorescence-based assay to screen antiviral drugs against Kaposi’s sarcoma-associated herpesvirus. Molecular Cancer Therapeutics, 2007, 6, 2360-2370.
  41. Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Asgari Z, Hooper AT, La Perle KMD, Hilsher C, Gao S-J, Dittmer D, Rafii S and Mesri EA. In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi’s sarcoma. Cancer Cell, 2007, 11, 245-258.
  42. Ye FC, Blackbourn DJ, Mengel M, Xie JP, Qian LW, Greene W, Yeh I-T, Graham D, and Gao S-J*. Kaposi’s sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1. Journal of Virology, 2007, 81, 3980-3991.
  43. Majerciak M, Pripuzova N, McCoy JP, Gao S-J and Zheng Z-M. Targeted disruption of KSHV ORF57 in the viral genome is detrimental for the expression of ORF59, K8, and K8.1 and the production of infectious virus. Journal of Virology, 2007, 81, 1062-1071.
  44. Zhu FX, Li XJ, Zhou FC, Gao S-J and Yan Yuan. Functional characterization of Kaposi’s sarcoma-associated herpesvirus ORF45 by BAC-based mutagenesis. Journal of Virology, 2006, 80, 12187-12196.
  45. Nair P, Pan HY, Stallings RL and Gao S-J. Recurrent genomic imbalances in primary effusion lymphomas. Cancer Genetics and Cytogenetics. 2006, 171, 119-121.
  46. Pan HY, Xie JP, Ye FC, and Gao S-J*. Modulation of KSHV infection and replication by MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways during primary infection. Journal of Virology, 2006, 80, 5371-5382.
  47. Lu F, Day L, Gao S-J, and Lieberman PM. Acetylation of the latency-associated nuclear antigen regulates repression of Kaposi’s sarcoma-associated herpesvirus lytic transcription. Journal of Virology, 2006, 80, 5273-5282.
  48. Fang Q, Liu J, Bai ZQ, Kang T, He ZH, Hu ZH, Gao SJ*. KSHV seroprevalence in the general population of Hubei in China. Virologica Sinica, 2006, 21, 97-101.
  49. Xie JP, Pan HY, Yoo SM and Gao S-J*. Induction of AP-1 and interleukin 6 during KSHV primary infection mediated by multiple MAPK pathways. Journal of Virology, 2005, 79, 15027-15037.
  50. Yoo SM, Zhou FC, Ye FC, Pan HY and Gao S-J*. Early and sustained expression of latent and host modulating genes in coordinated transcriptional program of KSHV productive primary infection of human primary endothelial cells. Virology, 2005, 343, 47-64.
  51. Krishnan HH, Sharma-Wali N, Zeng L, Gao S-J and Chandran B. Envelope glycoprotein B of Kaposi’s sarcoma-associated herpesvirus (KSHV) is essential for egress from infected cells. Journal of Virology, 2005, 79, 10952-10967.
  52. Si MW, Jagirdar J, Zhang YJ, Gao S-J, and Yeh TI. Detection of KSHV in transbronchial biopsies in patients with Kaposi’s sarcoma. Applied Immunohistochemistry and Molecular Morphology, 2005, 13, 61-65.
  53. Deng JH, Zhang YJ, Wang XP and Gao S-J*. Lytic replication-defective Kaposi’s sarcoma-associated herpesvirus (KSHV): potential role in infection and malignant transformation. Journal of Virology, 2004, 78, 11108-11120.
  54. Pan H-Y, Zhou FC, Gao S-J*. KSHV infection induces abnormal centrosome duplication and chromosome instability. Cancer Research, 2004, 64, 4064-4068.
  55. Ye FC, Zhou FC, Yoo SM, Xie JP and Gao S-J*. Disruption of Kaposi’s sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence. Journal of Virology, 2004, 78, 11121-11129.
  56. Luna RE, Zhou FC, Baghian A, Chouljenko V, Forghani V, Gao S-J, Kousoulas KG. Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is dispensable for viral entry and may facilitate virion egress. Journal of Virology, 2004, 78, 6389-6398.
  57. Baillargeon J, Pollock BH, Leach CT, and Gao S-J. The association of neoplasms and HIV infection in the correctional setting. International Journal of STD and AIDS, 2004, 15, 348-51.
  58. Gao, S-J*, J. H. Deng, and Zhou, F. C. Productive lytic replication of a recombinant KSHV in efficient primary infection in primary human endothelial cells. Journal of Virology, 2003; 77, 9738-49. (Journal Cover Article).
  59. Pan HY, Zhou FC, Wang XP, Zhang Y-J, Deng JH, Gao S-J*. Identification and characterization of a novel transcriptional repressor interacting with KSHV latent nuclear antigen. 2003; Journal of Virology, 2003, 77, 9758-68.
  60. Wang XP and Gao S-J*. Auto-activation of the oncogene viral interferon regulatory factor of Kaposi’s sarcoma-associated herpesvirus. Journal of General Virology 2003; 84, 329-36.
  61. Zhou FC, Wang XP, Zhang Y-J, Deng JH, Pan HY, Gao S-J*. Efficient infection of recombinant Kaposi’s sarcoma-associated herpesvirus cloned in bacteria artificial chromosome: application for genetic analysis. Journal of Virology, 2002; 76, 6185-96.
  62. Wang XP, Zhang Y-J, Deng JH, Pan HY, Zhou FC, Gao S-J*. Transcriptional regulation of KSHV-encoded oncogene viral interferon regulatory factor by a novel transcriptional silencer, Tis. The Journal of Biological Chemistry, 2002; 277, 12023-31.
  63. Baillargeon J, Leach CT, Deng JH, Gao S-J, Jenson HB. High prevalence of human herpesvirus 8 (HHV-8) infection in South Texas children. Journal of Medical Virology, 2002; 67, 524-8.
  64. Jenson HB, Ench Y, Zhang YJ, Gao S-J, Arrand JR, Mackett M: Characterization of an Epstein-Barr-related gammaherpesvirus from common marmoset (Callithrix jacchus). Journal of General Virology, 2002; 83, 1621-33.
  65. Zhang YJ, Pan HY, Gao S-J*. Reverse-transcription slippage over the mRNA secondary structure of the LIP1 gene. Biotechniques 2001; 31, 1286-1294.
  66. Baillargeon J, Deng JH, Hettler E, Harrison C, Grady JJ, Korte LJ, Alexander J, Montalvo EA, Jenson HB, Gao S-J*. Seroprevalence of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection among blood donors from Texas. Annals of Epidemiology 2001; 11, 512-8.
  67. Zhang YJ, Davis T, Deng JH, Wang XP, Baillargeon J, Yeh T, Jenson H, Gao S-J*. Distinct distribution of rare US KSHV genotypes in South Texas: implication for KSHV epidemiology and evolution. The Journal of Infectious Diseases 2001; 183, 125-9.
  68. Zhang YJ, Wang XP, Deng JH, Salinas RA, Oishi N, Gao S-J*. Suppression of KSHV-encoded oncogene viral interferon regulatory factor (vIRF) by ribozyme-mediated cleavage. Cancer Gene Therapy 2001; 8, 285-93.
  69. Wang XP, Zhang Y-J, Deng JH, Montalvo EA, Gao S-J*. Characterization of the promoter region of the viral interferon regulatory factor encoded by Kaposi’s sarcoma-associated herpesvirus. Oncogene 2001; 20, 523-530.
  70. Raje N, Kica G, Chauhan D, Zhang YN, Teoh G, Treon SP, Hideshima T, Deng JH, Gao S-J, Alsina M, Wally J, Pinkus GS, Pinkus JL, Skinner M, Comenzo RL, Anderson KC. Kaposi’s sarcoma-associated herpesvirus gene sequences are detectable at low copy number in primary amyloidosis. International Journal of Experimental and Clinical Investigation-Amyloid 2000; 7, 126-32.
  71. Jenson HB, Ench Y, Gao S-J, Rice K, Carey D, Kennedy RC, Arrand JR, Mackett M. Epidemiology of Herpesvirus papio infection in a large captive baboon colony and similarities to Epstein-Barr virus infection in humans. The Journal of Infectious Diseases 2000;181, 1462-6.
  72. Jenson HB, McClain KL, Leach CT, Deng J-H, Gao S-J. Evaluation of human herpesvirus type 8 infection in childhood Langerhans cell histiocytosis. American Journal of Hematology 2000; 64, 237-41.
  73. Oyajubi K, Deng JH, Dallas SL, Radl J, Jeson HB, Mundy GR, Gao S-J*. Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma. British Journal of Haematology 2000;109, 413-19.
  74. Zhang YJ, Deng JH, Rabkin C, Gao S-J*. Hot-spot variations of KSHV latent nuclear antigen (LNA) and application in genotyping by PCR-restriction fragment length polymorphism. Journal of General Virology 2000; 81, 2049-58.
  75. Wang HQ, Zhou B, Zhao XY, Zhang XH, Shen YC, Gao S-J. Serologic survey of Kaposi’s sarcoma-associated herpesvirus infection in intravenous drug users in China. National Medical Journal of China 2000; 80, 597-8.
  76. Gao S-J*, Zhang YJ, Deng JH, Rabkin, CS, Flore O, Jenson H. Molecular polymorphism of KSHV/HHV8 latent nuclear antigen: evidence for a large repertoire of viral genotypes and dual infection with different viral genotypes. The Journal of Infectious Diseases 1999;180, 1466-76.
  77. Leach CT, Frantz C, Head DR, Gao S-J, McClain KL, Cohen, M, Campell AB, Pollock, BH, Murphy SB, Jenson HB. Human herpesvirus-8 (HHV-8) associated with small non-cleaved cell lymphoma in a child with AIDS. American Journal of Hematology 1999;60, 215-21.
  78. Grulich AE, Olsen SJ, Luo K, Henry O, Cunningham P, Cooper D, Gao S-J, Chang Y, Moore PS, Kaldor JM. Kaposi’s sarcoma-associated herpesvirus: a sexually transmissible infection. The Journal of Acquired Immune Deficiency Syndromes Human Retrovirology 1999;20, 387-93.
  79. Gao S-J*, Alssina M, Deng J-H, Montalvo EA, Leach CT, Harrison C, Roodman DG & Jenson HB. Antibodies to Kaposi’s sarcoma-associated herpesvirus (human herpesvirus 8) in patients with multiple myeloma. The Journal of Infectious Diseases 1998;178, 846-9.
  80. Boshoff C, Gao S-J, Healy L, Matthews S, Thomas A, Coignet L, Warnke R, Strauchen J, Matutes E, Kamel OW, Moore PS, Weiss RA, Chang Y. Establishing a KSHV+ Cell Line (BCP-1) From Peripheral Blood and Characterizing Its Growth in Nod/SCID Mice. Blood, 1998;91, 1671-7.
  81. Flore O, Gao S-J. 1997 Effects of DNA synthesis inhibitors on KSHV cyclin and major capsid protein (MCP) gene expression. AIDS Research and Human Retroviruses 1997;13:1229-1233.
  82. Rainbow L, Platt GM, Simpson GR, Sarid R, Gao S-J, Stoiber H, Moore PS, Schulz TS. The 226/236 kD latent nuclear antigen (LNA) of Kaposi’s sarcoma associated herpesvirus (KSHV/HHV8) is encoded by ORF 73. Journal of Virology 1997;71:5915-21.
  83. Parravicini C, Olsen S, Capra M, Poli F, Sirchia G, Gao S-J, Berli E, Rossi E, Bestetti G, Pizzuto M, Galli M, Moroni M, Moore P, Corbellino M. Risk of Kaposi’s sarcoma-associated herpes virus transmission from donor allografts among Italian posttransplant Kaposi’s sarcoma patients. Blood 1997;90, 2826-9.
  84. Gao S-J, Chris Boshoff, Robin A. Weiss, Chang Y, Moore PS. KSHV vIRF is an oncogene that inhibits the interferon-signaling pathway. Oncogene 1997;15, 1979-85.
  85. Gao S-J*, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, Phair J, Detels R, Parry P, Chang Y, Moore PS*. Seroconversion of antibodies to Kaposi’s sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi’s sarcoma. The New England Journal of Medicine 1996;335:233-41. (With Editorial Comments and News in Science).
  86. Miller G, Rigsby M, Heston L, Grogan B, Sun R, Metroka C, Levy J, Gao S-J, Moore PS, Chang Y. Antibodies to butyrate-inducible antigens of Kaposi’s sarcoma-associated herpesvirus in patients with HIV-1 infection. The New England Journal of Medicine 1996;334:1292-7.
  87. Simpson GR, Schulz TF, Cook PM, Rainbow L, Howard M, Whitby D, Gao S J, Bohenzky RA, Simmonds P, Hatzakis A, Weller IVD, Moore PS. Prevalence of Kaposi’s sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 1996;348:1133-8.
  88. Moore PS, Gao S-J, Dominguez G, Cesarman E, Lungu O, Knowles DM, Garber R, Pellet P, McGeoch DJ, Chang Y. Primary characterization of a herpesviral agent associated with Kaposi’s sarcoma. Journal of Virology 1996;70:549-58.
  89. Gao S-J, Kingsley L, Li M, Zheng W, Parravicini C, Ziegler J, Newton R, Rinaldo CR, Saah A, Phair J, Detels R, Chang Y, Moore PS. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi’s sarcoma. Nature Medicine 1996;2:925-8. (With Editorial Comments and News in Science and Nature Medicine, and cited as a classic and ranged the 3th most important articles in the infectious disease category in the 10th Year Anniversary of Nature Medicine: http://www.nature.com/nm/special_focus/anniversary/>infectious.html).

    90.  
    Bioinformatics original basic works:

    1. Cui J, Petritis K, Tegeler T, Petritis B, Ma XP, Jin YF, Gao SJ, Zhang JQ. Accurate LC peak boundary detection for 16O/18O labeled LC-MS data. PLoS ONE, 2013, 8(10): e72951. doi:10.1371/journal.pone.0072951.
    2. Nguyen N, Chiao YA, Huang YF, Gao SJ, Lindsey M, Chen YD, Jin YF. Temporal clustering of gene expression patterns using short-time segments. International Journal of Functional Informatics and Personalised Medicine, 2012, 4, 32-46.
    3. Liu H, Yue D, Zhang L, Chen YD, Gao S-J, Huang YF. Improving performance of mammalian microRNA target prediction. BMC Bioinformatics, 2010, 11:476.
    4. Meng J, Lu MZ, Gao S-J, Chen YD, Huang YF, Robust inference of the context specific structure and temporal dynamics of gene regulatory network. BMC Genomics, 2010, 11 Suppl 3:S11.
    5. Liu H, Yue D, Zhang L, Chen YD, Gao S-J and Huang YF. A Bayesian approach for identifying miRNA targets by combining sequence prediction and expression profiling. BMC Genomics, 2010, 11 Suppl 3:S12.
    6. Yue D, Chen YD, Gao S-J, Huang YF. Computational prediction of microRNA regulatory pathways. Proceedings – 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing, IJCBS 2009, art. no. 5260699, 185-189.
    7. Nyuyen N, Jin Y, Huang Y, Chiao YA, Gao S-J, Lindsey M, Chen Y. Temporal clustering of gene expression patterns using short-time segments. Proceedings – 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing, IJCBS 2009, art. no. 5703794, 173-178.
    8. Meng J, Gao S-J, Huang YF. Enrichment constrained time-dependent clustering analysis for finding meaningful temporal transcription modules. Bioinformatics, 2009, 25, 1521-1527.
    9. Liu H, Zhang L, Gao S-J and Huang YF. A Bayesian approach for Identifying miRNA targets by combining sequence prediction and expression profiling. IEEE Xplore, 2009, 185-189.
    10. Meng J, Gao S-J, Huang YF. An Iterative time window signature algorithm for time-dependent transcription module discovery. IEEE Workshop Genomic Signal Processing and Statistics (GENSiPS), 2008, 1-4.
    11. Liu H, Yue D, Zhang L, Gao S-J, Huang YF. A machine learning approach for miRNA target prediction. IEEE Workshop Genomic Signal Processing and Statistics (GENSiPS), 2008, 1-3.

     
    Reviews

    1. He ML, Gao SJ*. A novel role of SIRT1 in gammaherpesvirus latency and replication, Cell Cycle, 2014, 13, 3328-3330.
    2. Zhu Y, Huang YF, Jung JU, Lu C, Gao S-J*. Viral miRNA targeting of bicistronic and polycistronic transcripts. Current Opinion in Virology, 2014, 7C, 66-72.
    3. Zhu Y, Haecker I, Yang Y, Gao S-J, Renne R. γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis. Current Opinion in Virology. 2013, 3, 266-275.
    4. Zhang W, Gao SJ*. Exploitation of cellular cytoskeletons and signaling pathways for cell entry by Kaposi’s sarcoma-associated herpesvirus and the closely related rhesus rhadinovirus. Pathogens, 2012, 1, 201-127.
    5. Ye FC* and Gao S-J*. A Novel role of hydrogen peroxide in Kaposi’s sarcoma-associated herpesvirus reactivation. Cell Cycle, 2011, 10, 3237-3238.
    6. Ye FC*, Lei XF, and Gao S-J*. Mechanisms of Kaposi’s sarcoma-associated herpesvirus latency and reactivation. Advances in Virology, 2011, Article ID: 193860.
    7. Zhou FC and Gao S-J*. Recent advances in cloning herpesviral genomes as infectious bacterial artificial chromosomes. Cell Cycle, 2011, 10, 434-440.
    8. Sarid R* and Gao S-J* Viruses and human cancer: from detection to causality. Cancer Letters, 2011, 305, 218-227.
    9. Lei XF, Ye FC, Bai ZQ, Huang YF and Gao S-J*. Regulation of herpesvirus lifecycle by viral microRNAs. Virulence, 2010, 1, 433-435.
    10. Lei XF, Bai ZQ, Ye FC, Huang YF and Gao S-J*. MicroRNAs control herpesviral dormancy. Cell Cycle, 2010, 9 (7), 1225-1226 (“FEATURE” article).
    11. Kang T, Ye FC, Gao S-J* and Wang LD*. Angiogenesis, Kaposi’s sarcoma and Kaposi’s sarcoma-associated herpesvirus. Virologica Sinica, 2008, 23, 449-458.
    12. Bai ZQ, Lei XF, Wang LD* and Gao S-J*. Identification and function of microRNAs encoded by herpesviruses. Virologica Sinica, 2008, 23, 459-472.
    13. Greene W, Kuhne K, Ye FC, Chen JG, Zhou FC, Lei XF, and Gao S-J*. Molecular biology of KSHV in relation to AIDS-associated oncogenesis. In: AIDS-Associated Viral Oncogenesis, Cancer Treatment and Research Book Series. Volume 133, 2007, pp: 69-127. Craig Meyers (Ed.). Springer US Science+Business Media. 978-0-387-46816-7 (Online) ISBN: 978-0-387-46804-4 (Print). (Review and Comments in New England Journal of Medicine 2008, 358, 98).
    14. Gao S-J*, Moore PS*. Molecular approaches to the identification of unculturable infectious agents. Emerging Infectious Diseases, 1996;2:159-67.
    15. Gao S-J*. PCR Protocols for Emerging Infectious Diseases, Persing DH (ed). ASM Press. Trends in Microbiology, 1997;5:125-6. (Book review)

     
    Other research works:

    1. Gao S-J, Garnier M, Bové JM. Production of monoclonal antibodies recognizing most Asian stains of the greening BLO by in vitro immunization with an antigenic protein purified from the BLO. Proceedings of International Organization of Citrus Virologists 1993;12:244-9.
    2. Garnier M, Gao S-J, He Y-L, Villenchanoux S, Bové JM. Study of the greening organism (GO) with monoclonal antibodies: serological identification, morphology, serotypes and purification of the GO. Proceedings of International Organization of Citrus Virologists 11:1991, 428-35 (J. Merrill and Adeline Wallace Award for Outstanding Paper).
    3. Gao S-J, Chen S-S, Li M-Q. The problem of HCO3- concentration in measuring photosynthesis with an oxygen electrode. Plant Physiology Communications 1989;3:52-3.
    4. Gao S-J, Chen S-S, Li M-Q. Effect of phosphorus nutrition on photosynthesis and photorespiration in tobacco leaves. Acta Phytophysiologica Sinica 1989;15:281-7.
    5. Li M-Q, Gao S-J, Chen S-S. Rapid post-illumination oxygen consumption and its relation to photorespiration. Acta Phytophysiologica Sinica 1988; 14:313-17.
    6. Gao S-J, Moore PS, Chang Y. BCP-1: a Kaposi’s sarcoma-associated herpesvirus (KSHV or HHV8) infected cell line isolated from the peripheral blood mononuclear cells of a HIV-seronegative patients with body cavity-based (primary effusion) lymphoma (BCBL or PEL). American Type Culture Collection (ATCC): CRL-2294, 1996.
    7. Gao S-J. Production of monoclonal antibodies against the bacteria-like organism associated with citrus greening disease in Fujian, China. UNDP-FAO Report (RAS/86/022), 1989. 18p.