20150522_132554

The Yuan lab investigates the molecular mechanism and regulation of CD1d antigen presentation and NKT cell function during anti-viral and anti-tumor immune responses.

  1. We established the first humanized mouse model system with CD1d/NKT cell lipid presentation.
  2. We discovered a novel immune evasion mechanism by herpes simplex virus-1 that targets CD1d/NKT antigen presentation.