Post-Doctoral Fellows

DSC_0285Morgan Chateau, PhD

mchateau@usc.edu

B.S. Genetics and Biochemistry, Texas A&M University
Ph.D. Microbiology and Immunology, University of North Carolina

Research: I study humanized mice in the context of HIV, gene-editing, AAV vectors and B-cell development.

Hobbies: Circus art (trapeze, contortion, hand-balancing), rock climbing, and my cat

 

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Danielle Krasner, PhD

dkrasner@usc.edu

B.S. Biochemistry, CSULA
Ph.D. Molecular Biophysics and Biochemistry, Yale

Research: I am studying methods of improving gene editing efficiencies in hematopoietic stem cells by increasing the rates of homologous recombination through the modulation of factors involved in DNA repair. Additionally, I am working to characterize these DNA repair mechanisms in HSCs following the introduction of a DNA double strand break.

Hobbies: Rock climbing, circus, scuba diving, and general adventure-ing

 

Nick Llewellyn, PhDDSC_0201          

gllewell@usc.edu

B.S. Biochemistry, University of Washington
Ph.D. Molecular and Cellular Biology, University of Michigan

Research: I am developing humanized mouse models to study HIV, specifically latency and infection of microglia in the brain. I am also developing tools to disrupt latent HIV e.g. anti-HIV nucleases such as TALENs and lentiviral vectors specifically targeted to latently infected cells. Lastly, I work on reducing off target effects of TALENs through use of non-canonical repeat variable di-nucleotides (RVDs).

Hobbies: Tennis, video games and spinning fire at Burning Man

 

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Geoffrey Rogers, PhD

rogersg@usc.edu

B.S. Molecular Biology, University of California, San Diego
Ph.D. Immunology and Microbiology, University of Florida

Research: I am investigating the use of genetic engineering to express broadly-neutralizing anti-HIV antibodies within B cells. I am also working on developing AAV vectors for in vivo modification of hematopoietic stem cells.

Hobbies: Cooking, and pairing wine with food

 

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Eduardo Seclen, PhD

seclen@usc.edu

B.S. Biotechnology and Medical Biology, Complutense University of Madrid
Ph.D. Medical Microbiology, Complutense University of Madrid

Research: I’m currently developing non-toxic methods for gene therapy in hematopoietic stem cells (HSC), specifically using the ZFN and CRISPR-Cas9 systems. I am also focused in improving gene therapy by: 1. Increasing HSC engraftment capabilities of modified and non-modified HSC. 2. Increasing homologous recombination as a preferential repair pathway for safe gene insertions. 3. Alleviating toxicity associated with gene therapy in primary cells by regulating DNA sensing pathways.

Hobbies: Soccer, Capoeira and bars

 

DSC_0206Cathy Wang, PhD

cathyxuw@usc.edu

B.S. Biochemistry, University of Alberta
Ph.D. Scripps Research Institute

Research: I am using genome editing tools to engineer more potent anti-HIV restriction factors in hematopoietic stem cells, as a novel form of HIV gene therapy. I am also studying changes in the hematopoietic stem cell transcriptome in response to different genome editing platforms. Finally, I am interested in in vivo targeted transduction of hematopoietic stem cells using viral vectors.

Hobbies: Bike riding, national parks, board games