Morgan Chateau, PhD
Education: Texas A&M University, B.S. Genetics and Biochemistry;
University of North Carolina, Ph.D. Microbiology and Immunology
Research: I study humanized mice in the context of HIV, gene-editing, AAV vectors and B-cell development.
Hobbies: Circus art (trapeze, contortion, hand-balancing), rock climbing, and my cat
Danielle Krasner, PhD
Education: CSULA, B.S. Biochemistry; Yale, Ph.D. Molecular Biophysics and Biochemistry
Research: I am studying methods of improving gene editing efficiencies in hematopoietic stem cells by increasing the rates of homologous recombination through the modulation of factors involved in DNA repair. Additionally, I am working to characterize these DNA repair mechanisms in HSCs following the introduction of a DNA double strand break.
Hobbies: Rock climbing, circus, scuba diving, and general adventure-ing
Nick Llewellyn, PhD
Education: University of Washington, B.S. Biochemistry; University of Michigan, Ph.D. Molecular and Cellular Biology
Research: I am developing humanized mouse models to study HIV, specifically latency and infection of microglia in the brain. I am also developing tools to disrupt latent HIV e.g. anti-HIV nucleases such as TALENs and lentiviral vectors specifically targeted to latently infected cells. Lastly, I work on reducing off target effects of TALENs through use of non-canonical repeat variable di-nucleotides (RVDs).
Hobbies: Tennis, video games and spinning fire at Burning Man
Geoffrey Rogers, PhD
Education: UC San Diego, B.S. Molecular Biology; University of Florida, Ph.D. Immunology and Microbiology
Research: I am investigating the use of genetic engineering to express broadly-neutralizing anti-HIV antibodies within B cells. I am also working on developing AAV vectors for in vivo modification of hematopoietic stem cells.
Hobbies: Cooking, and pairing wine with food
Eduardo Seclen, PhD
Education: Complutense University of Madrid, B.S. Biotechnology and Medical Biology, Ph.D. Medical Microbiology
Research: I’m currently developing non-toxic methods for gene therapy in hematopoietic stem cells (HSC), specifically using the ZFN and CRISPR-Cas9 systems. I am also focused in improving gene therapy by: 1. Increasing HSC engraftment capabilities of modified and non-modified HSC. 2. Increasing homologous recombination as a preferential repair pathway for safe gene insertions. 3. Alleviating toxicity associated with gene therapy in primary cells by regulating DNA sensing pathways.
Hobbies: Soccer, Capoeira and bars
Cathy Wang, PhD
Education: University of Alberta, B.S. Biochemistry; Scripps Research Institute, Ph.D. Biology
Research: I am using genome editing tools to engineer more potent anti-HIV restriction factors in hematopoietic stem cells, as a novel form of HIV gene therapy. I am also studying changes in the hematopoietic stem cell transcriptome in response to different genome editing platforms. Finally, I am interested in in vivo targeted transduction of hematopoietic stem cells using viral vectors.
Hobbies: Bike riding, national parks, board games