I-Chueh Huang LabKeck School of Medicine, USC

I-Chueh Huang Lab

Keck School of Medicine, USC

Publications

  1. Chiu WY, Yang CC, Huang IC, Huang TS. 2004. Dysphagia as a manifestation of thyrotoxicosis: report of three cases and literature review. ; 19(2):120-4.
  1. Li W, Zhang C, Sui J, Kuhn JH, Moore MJ, Luo S, Wong SK, Huang IC, Xu K, Vasilieva N, Murakami A, He Y, Marasco WA, Guan Y, Choe H, Farzan M. 2005. Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J.; 24(8):1634-43.
  1. Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H. 2006. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem.; 281(6):3198-203.
  1. Huang IC, Bosch BJ, Li W, Farzan M, Rottier PM, Choe H. 2006. SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry. Adv Exp Med Biol.; 581:335-8.
  1. Li W, Wong SK, Li F, Kuhn JH, Huang IC, Choe H, Farzan M. 2006. Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol.; 80(9):4211-9.
  1. Li W, Sui J, Huang IC, Kuhn JH, Radoshitzky SR, Marasco WA, Choe H, Farzan M. 2007. The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2. ; 367(2):367-74.
  1. Huang IC, Li W, Sui J, Marasco W, Choe H, Farzan M. 2008. Influenza A virus neuraminidase limits viral superinfection. J Virol.; 82(10):4834-43.
  1. Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A. 2009. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe.; 8;5(5):439-49.
  1. Brass AL*, Huang IC*, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ. 2009. The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell; 139(7):1243-54. *equal author.
  1. Huang IC*, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. 2011. Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus. PLoS Pathog.; 7(1):e1001258. *corresponding author.
  1. Chan YK, Huang IC, Farzan M. 2012. IFITM proteins restrict antibody-dependent enhancement of dengue virus infection. PLoS One; 7(3):e34508.
  1. Bailey CC, Huang IC, Kam C, Farzan M. 2012. Ifitm3 limits the severity of acute influenza in mice. PLoS Pathog.; 8(9):e1002909.
  1. Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC. 2013. Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. PLoS One; 8(4):e60838.
  1. Amini-Bavil-Olyaee S, Choi YJ, Lee JH, Shi M, Huang IC, Farzan M, Jung JU. 2013. The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry. Cell Host Microbe.; 13(4):452-64.
  1. Mudhasani R, Tran JP, Retterer C, Radoshitzky SR, Kota K, Altamura LA, Smith JM, Packard BZ, Kuhn JH, Costantino J, Garrison AR, Schmaljohn CS, Huang IC, Farzan M, Bavari S. 2013. IFITM-2 and IFITM-3 but not IFITM-1 restrict rift valley fever virus. J Virol.; 7(15):8451-64.
  1. Bailey CC, Kondur HR, Huang IC, Farzan M. 2013. Interferon-induced transmembrane protein 3 is a type II transmembrane protein. J Biol Chem.; 288(45):32184-93.
  1. Warren CJ, Griffin LM, Little AS, Huang IC, Farzan M, Pyeon D. 2014. The antiviral restriction factors ifitm1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS One; 14;9(5):e96579.
  1. Bailey CC, Zhong G, Huang IC, Farzan M. 2014. IFITM-Family Proteins: The cell’s first line of antiviral defense. Annu Rev Virol.; 1: 261-283.
  1. Williams DEJ, Wu WL, Grotefend CR, Nguyen NT, Chung C, Chung YH, Farzan M, Huang IC. 2014. IFITM3 polymorphism rs12252-C restricts influenza A viruses. PLoS One ;9(10):e110096.