{"id":21,"date":"2014-09-26T22:54:26","date_gmt":"2014-09-27T05:54:26","guid":{"rendered":"http:\/\/old.uscmmi.com\/omidakbarilab\/?page_id=21"},"modified":"2026-01-29T14:50:24","modified_gmt":"2026-01-29T22:50:24","slug":"publications","status":"publish","type":"page","link":"http:\/\/uscmmi.com\/omidakbarilab\/?page_id=21","title":{"rendered":"Publications"},"content":{"rendered":"<h6><strong>2025<\/strong><\/h6>\n<ul>\n<li><strong>Barbetta, A. et al.<\/strong>\u00a0Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite.\u00a0<em>Scientific Reports<\/em>\u00a015, 9394 (2025).<\/li>\n<li><strong>Cain, J., Hurrell, B. &amp; Akbari, O.<\/strong>\u00a0The Expanding Role of ILC2s in Allergic Airways Disease.\u00a0<em>Allergy<\/em>(2025).<\/li>\n<li><strong>Chandan, G. et al.<\/strong>\u00a0Perinatal Flavored E-cigarette Exposure and the Critical Role of Innate Lymphoid type II Cells in Transgenerational Asthma Transmission.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0155, AB442 (2025).<\/li>\n<li><strong>Chandan, G. et al.<\/strong>\u00a0Transgenerational Asthma Risk Induced by Perinatal E-cigarette Exposure: Role of Pulmonary Innate Lymphoid Type II Cells.\u00a0<em>American Journal of Respiratory and Critical Care Medicine<\/em>211, A3436-A3436 (2025).<\/li>\n<li><strong>Hempel, S. et al.<\/strong>\u00a0Multiple chemical sensitivity (MCS) validity, prevalence, tools and interventions: systematic review protocol.\u00a0<em>BMJ open<\/em>\u00a015, e088136 (2025).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0The hidden role of iron: unlocking new therapies for asthma and beyond 9432.\u00a0<em>The Journal of Immunology<\/em>\u00a0214, vkaf283. 2831 (2025).<\/li>\n<li><strong>Kazemi, M.H. et al.<\/strong>\u00a0FOXO1 pathway activation by VISTA immune checkpoint restrains pulmonary ILC2 functions.\u00a0<em>The Journal of Clinical Investigation<\/em>\u00a0135 (2025).<\/li>\n<li><strong>Kazemi, M.H. et al.<\/strong>\u00a0VISTA regulates lung ILC2 metabolism and effector function through FOXO1 2223.\u00a0<em>The Journal of Immunology<\/em>\u00a0214, vkaf283. 166 (2025).<\/li>\n<li><strong>Lotfi, N. et al.<\/strong>\u00a0Enhancing Lung Autophagy Could be a Preventive Strategy Against Maternal E-Cigarette-Associated Offspring Pulmonary Morbidity.\u00a0<em>Journal Of Investigative Medicine<\/em>\u00a02025: Sage Publications Ltd; 2025. P. 80-81.<\/li>\n<li><strong>Lotfi, N. et al.<\/strong>\u00a0Improving Lung Autophagy May Serve as a Potential Approach to Reducing Chronic Pulmonary Diseases Associated With Exposure to E-cigarettes.\u00a0<em>American Journal of Respiratory and Critical Care Medicine<\/em>\u00a0211, A3403-A3403 (2025).<\/li>\n<li><strong>Prins, R., Fernandez, D.J., Akbari, O., Da Silva, D.M. &amp; Kast, W.M.<\/strong>\u00a0HPV16 E6 and E7 expressing cancer cells suppress the antitumor immune response by upregulating KLF2-mediated IL-23 expression in macrophages.\u00a0<em>Journal for Immunotherapy of Cancer<\/em>\u00a013, e011915 (2025).<\/li>\n<li><strong>Quach, C. et al.<\/strong>\u00a0BTLA agonist attenuates Th17-driven inflammation in a mouse model of steroid-resistant asthma.\u00a0<em>Frontiers in Immunology<\/em>\u00a016, 1552394 (2025).<\/li>\n<li><strong>Sakano, K. et al.<\/strong>\u00a0Targeting CD48 Ameliorates ILC2-mediated Airway Hyperreactivity by Disrupting the PKC\u03b2 Pathway.\u00a0<em>American Journal of Respiratory Cell and Molecular Biology<\/em>\u00a0(2025).<\/li>\n<li><strong>Sakano, K. et al.<\/strong>\u00a0CD48 regulates ILC2 effector function and lung inflammation through the PKC\u00df pathway 2049.\u00a0<em>The Journal of Immunology<\/em>\u00a0214, vkaf283. 019 (2025).<\/li>\n<li><strong>Sakano, Y. et al.<\/strong>\u00a0The potential of signal regulatory protein alpha as a therapeutic target for airway hyperreactivity 9433.\u00a0<em>The Journal of Immunology<\/em>\u00a0214, vkaf283. 2832 (2025).<\/li>\n<li><strong>Sakano, Y. et al.<\/strong>\u00a0ICOS regulates IL-10 production in group 2 innate lymphoid cells via cholesterol and cortisol biosynthesis.\u00a0<em>The Journal of Clinical Investigation<\/em>\u00a0135 (2025).<\/li>\n<li><strong>Shen, S., Li, X., Hurrell, B.P., Sakano, Y. &amp; Akbari, O.<\/strong>\u00a0Piezo1 channels orchestrate ILC2-dependent lung inflammation and development of airway hyperreactivity 9431.\u00a0<em>The Journal of Immunology<\/em>\u00a0214, vkaf283. 2830 (2025).<\/li>\n<\/ul>\n<p><strong>2024<\/strong><\/p>\n<ul>\n<li><strong>Aguilar, D. et al.<\/strong>\u00a0Sensory neurons regulate stimulus-dependent humoral immunity.\u00a0<em>bioRxiv<\/em>, 2024.2001. 2004.574231 (2024).<\/li>\n<li><strong>Aguilar, D. et al.<\/strong>\u00a0Sensory neurons regulate stimulus-dependent humoral immunity in mouse models of bacterial infection and asthma.\u00a0<em>Nature Communications<\/em>\u00a015, 8914 (2024).<\/li>\n<li><strong>Barbetta, A. et al.<\/strong>\u00a0IMmuneCite: an integrated workflow for analysis of immune enriched spatial proteomic data.\u00a0<em>Research Square<\/em>, rs. 3. rs-4571625 (2024).<\/li>\n<li><strong>Barbetta, A. et al.<\/strong>\u00a0Spatially resolved immune exhaustion within the alloreactive microenvironment predicts liver transplant rejection.\u00a0<em>Science Advances<\/em>\u00a010, eadm8841 (2024).<\/li>\n<li><strong>Chandan, G. et al.<\/strong>\u00a0Pulmonary Innate Lymphoid Type II Cells in Perinatal Vaping-induced Asthma in Offspring.\u00a0<em>American Thoracic Society<\/em>, 2024, Pp A6998-A6998.<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0Iron controls the development of airway hyperreactivity by regulating ILC2 metabolism and effector function.\u00a0<em>Science Translational Medicine<\/em>\u00a016, eadk4728 (2024).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity.\u00a0<em>Journal of Experimental Medicine<\/em>\u00a0221, e20231835 (2024).<\/li>\n<li><strong>Li, Y. et al.<\/strong>\u00a0Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages.\u00a0<em>PLoS Pathogens<\/em>\u00a020, e1012079 (2024).<\/li>\n<li><strong>Rocque, B. et al.<\/strong>\u00a0Technical optimization of spatially resolved single-cell transcriptomic datasets to study clinical liver disease.\u00a0<em>Scientific reports<\/em>\u00a014, 3612 (2024).<\/li>\n<li><strong>Sakano, Y. et al.<\/strong>\u00a0Blocking CD226 regulates ILC2 effector function and alleviates airway hyperreactivity: 440.\u00a0<em>Journal of Allergy &amp; Clinical Immunology<\/em>\u00a0153, AB141 (2024).<\/li>\n<li><strong>Sakano, Y. et al.<\/strong>\u00a0Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0153, 1406-1422. e1406 (2024).<\/li>\n<li><strong>Sakano, Y. et al.<\/strong>\u00a0SIRP\u03b1 engagement regulates ILC2 effector function and alleviates airway hyperreactivity via modulating energy metabolism.\u00a0<em>Cellular &amp; Molecular Immunology<\/em>\u00a021, 1158-1174 (2024).<\/li>\n<li><strong>Shafiei-Jahani, P. et al.<\/strong>\u00a0CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus.\u00a0<em>Cell reports<\/em>\u00a043 (2024).<\/li>\n<li><strong>Silverstein, A. et al.<\/strong>\u00a0Mitochondrial gene signatures illuminate mitochondrial function as an important contributor to post-COVID recovery and long COVID<\/li>\n<\/ul>\n<p><strong>2023<\/strong><\/p>\n<ul>\n<li><strong>Allan-Blitz, L.-T. et al.<\/strong>\u00a0Unique immune and inflammatory cytokine profiles may define long COVID syndrome.\u00a0<em>Clinical and Experimental Medicine<\/em>\u00a023, 2925-2930 (2023).<\/li>\n<li><strong>Allan-Blitz, L.-T., Goodrich, J., Hu, H., Akbari, O. &amp; Klausner, J.D.<\/strong>\u00a0Altered Tumor Necrosis Factor Response in Neurologic Postacute SARS-CoV-2 Syndrome.\u00a0<em>Journal of Interferon &amp; Cytokine Research<\/em>\u00a043, 307-313 (2023).<\/li>\n<li><strong>Barbers, R.G. et al.<\/strong>\u00a0ILC2s With Tnfr2 Expression Are Potential Therapeutic Targets For Asthma.\u00a0<em>Chest<\/em>\u00a0164, A4904 (2023).<\/li>\n<li><strong>Choi, Y.J. et al.<\/strong>\u00a0Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation.\u00a0<em>Nature communications<\/em>\u00a014, 2045 (2023).<\/li>\n<li><strong>Helou, D.G. et al.<\/strong>\u00a0Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0151, 526-538. e528 (2023).<\/li>\n<li><strong>Helou, D.G. et al.<\/strong>\u00a0LAIR-1 limits macrophage activation in acute inflammatory lung injury.\u00a0<em>Mucosal immunology<\/em>16, 788-800 (2023).<\/li>\n<li><strong>Hempel, S. et al.<\/strong>\u00a0Multiple chemical sensitivity scoping review protocol: overview of research and MCS construct.\u00a0<em>BMJ open<\/em>\u00a013, e072098 (2023).<\/li>\n<li><strong>Howard, E. et al.<\/strong>\u00a0Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models.\u00a0<em>Nature Communications<\/em>\u00a014, 5989 (2023).<\/li>\n<li><strong>Quach, C. et al.<\/strong>\u00a0Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome.\u00a0<em>Cell reports<\/em>\u00a042 (2023).<\/li>\n<\/ul>\n<p><strong>2022<\/strong><\/p>\n<ul>\n<li><strong>Galle-Treger, L. et al.<\/strong>\u00a0Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23.\u00a0<em>Nature Communications<\/em>\u00a013, 1440 (2022).<\/li>\n<li><strong>Helou, D.G. et al.<\/strong>\u00a0LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0149, 223-236. e226 (2022).<\/li>\n<li><strong>Helou, G.D. et al.<\/strong>\u00a0PD-1 agonist modulates ILC2 metabolism and ameliorates airway hyperreactivity.\u00a0<em>The Journal of Immunology<\/em>\u00a0208, 109.115-109.115 (2022).<\/li>\n<li><strong>Howard, E.D. et al.<\/strong>\u00a0PD-1 inhibition on pulmonary ILC2s promotes TNF-\u03b1 production and restricts progression of metastatic melanoma tumor growth.\u00a0<em>The Journal of Immunology<\/em>\u00a0208, 163.107-163.107 (2022).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability.\u00a0<em>Nature Communications<\/em>\u00a013, 5118 (2022).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0Cannabinoid receptor 2 engagement promotes group 2 innate lymphoid cell expansion and enhances airway hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0149, 1628-1642. e1610 (2022).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0CB2 engagement enhances group 2 innate lymphoid cell expansion and induction of airway hyperreactivity.\u00a0<em>The Journal of Immunology<\/em>\u00a0208, 109.114-109.114 (2022).<\/li>\n<li><strong>Li, Y., Lee, J., Helou, D.G., Akbari, O. &amp; Ou, J.-h.J.<\/strong>\u00a0Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model.\u00a0<em>STAR protocols<\/em>\u00a03, 101364 (2022).<\/li>\n<li><strong>Rahman, M.M. et al.<\/strong>\u00a0Near-roadway air pollution, immune cells and adipokines among obese young adults.\u00a0<em>Environmental Health<\/em>\u00a021, 36 (2022).<\/li>\n<li><strong>Rocque, B. et al.<\/strong>\u00a0Single Cell Multiomics Reveals Immune Mediators in Acute Cellular Rejection Following Pediatric Liver Transplantation.\u00a0<em>American Journal Of Transplantation<\/em>\u00a02022: Wiley. P. 538-538.<\/li>\n<li><strong>Sarode, D. et al.<\/strong>\u00a0Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation.\u00a0<em>American Journal Of Transplantation<\/em>\u00a02022: WILEY. p. 494-495.<\/li>\n<li><strong>Ung, N. et al.<\/strong>\u00a0Adaptation of imaging mass cytometry to explore the single cell alloimmune landscape of liver transplant rejection.\u00a0<em>Frontiers in immunology<\/em>\u00a013, 831103 (2022).<\/li>\n<\/ul>\n<p><strong>2021<\/strong><\/p>\n<ul>\n<li><strong>Baban, B. et al.<\/strong>\u00a0AMPK induces regulatory innate lymphoid cells after traumatic brain injury.\u00a0<em>JCI insight<\/em>\u00a06, e126766 (2021).<\/li>\n<li><strong>Emamaullee, J. et al.<\/strong>\u00a0Multiplexed Imaging Mass Cytometry of the Alloimmune Landscape of Rejection in Clinical Liver Transplantation.\u00a0<em>American Journal Of Transplantation<\/em>\u00a02021: Wiley. P. 348-348.<\/li>\n<li><strong>Hirose, S. et al.<\/strong>\u00a0Impact of a demyelination-inducing central nervous system virus on expression of demyelination genes in type 2 lymphoid cells.\u00a0<em>Journal of Virology<\/em>\u00a095, 10.1128\/jvi. 01934-01920 (2021).<\/li>\n<li><strong>Hirose, S. et al.<\/strong>\u00a0Correction for Hirose et al.,\u201cImpact of a Demyelination-Inducing Central Nervous System Virus on Expression of Demyelination Genes in Type 2 Lymphoid Cells\u201d.\u00a0<em>Journal of Virology<\/em>\u00a095, 10.1128\/jvi. 00209-00221 (2021).<\/li>\n<li><strong>Howard, E. et al.<\/strong>\u00a0PD-1 blockade on tumor microenvironment-resident ILC2s promotes TNF-\u03b1 production and restricts progression of metastatic melanoma.\u00a0<em>Frontiers in Immunology<\/em>\u00a012, 733136 (2021).<\/li>\n<li><strong>Howard, E. et al.<\/strong>\u00a0IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism, and ameliorates airway hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0147, 1281-1295. e1285 (2021).<\/li>\n<li><strong>Matundan, H.H., Jaggi, U., Yu, J., Akbari, O. &amp; Ghiasi, H.<\/strong>\u00a0Absence of CD28-CTLA4-PD-L1 costimulatory molecules reduces herpes simplex virus 1 reactivation.\u00a0<em>Mbio<\/em>\u00a012, 10.1128\/mbio. 01176-01121 (2021).<\/li>\n<li><strong>Painter, J.D. &amp; Akbari, O.<\/strong>\u00a0Type 2 innate lymphoid cells: protectors in type 2 diabetes.\u00a0<em>Frontiers in Immunology<\/em>12, 727008 (2021).<\/li>\n<li><strong>Rocque, B. et al.<\/strong>\u00a0Analysis of Single Cell RNA Sequencing Data to Define Biomarkers of Human Liver Immune Tolerance.\u00a0<em>American Journal Of Transplantation<\/em>\u00a02021: Wiley. P. 582-583.<\/li>\n<li><strong>Rocque, B. et al.<\/strong>\u00a0Creation of a single cell RNASeq meta-atlas to define human liver immune homeostasis.\u00a0<em>Frontiers in immunology<\/em>\u00a012, 679521 (2021).<\/li>\n<li><strong>Shafiei-Jahani, P. et al.<\/strong>\u00a0CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation.\u00a0<em>Mucosal immunology<\/em>\u00a014, 899-911 (2021).<\/li>\n<li><strong>Shafiei-Jahani, P. et al.<\/strong>\u00a0CD200\u2013CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma.\u00a0<em>Nature communications<\/em>\u00a012, 2526 (2021).<\/li>\n<\/ul>\n<p><strong>2020<\/strong><\/p>\n<ul>\n<li><strong>Emamaullee, J. et al.<\/strong>\u00a0Multiplexed Imaging Mass Cytometry Analysis Reveals a New Role for CD68+ Macrophages in Chronic Liver Transplant Rejection.\u00a0<em>American Journal Of Transplantation<\/em>\u00a02020: Wiley. P. 324-324.<\/li>\n<li><strong>Galle, L. et al.<\/strong>\u00a0Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function.\u00a0<em>The Journal of Immunology<\/em>\u00a0204, 147.143-147.143 (2020).<\/li>\n<li><strong>Galle-Treger, L. et al.<\/strong>\u00a0Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0145, 502-517. e505 (2020).<\/li>\n<li><strong>Gilmore, W. et al.<\/strong>\u00a0Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis.\u00a0<em>Journal of Neuroinflammation<\/em>\u00a017, 189 (2020).<\/li>\n<li><strong>Han, Y. et al.<\/strong>\u00a0Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.\u00a0<em>Nature communications<\/em>\u00a011, 1776 (2020).<\/li>\n<li><strong>Helou, D.G. et al.<\/strong>\u00a0PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity.\u00a0<em>Nature communications<\/em>\u00a011, 3998 (2020).<\/li>\n<li><strong>Hirose, S. et al.<\/strong>\u00a0Type 2 innate lymphoid cells induce CNS demyelination in an HSV-IL-2 mouse model of multiple sclerosis.\u00a0<em>Iscience<\/em>\u00a023 (2020).<\/li>\n<li><strong>Howard, E.D. et al.<\/strong>\u00a0Phenotype-driven screening of 150 strains of mice for allergic lung inflammation identified strains representative of heterogeneous human asthma cohorts.\u00a0<em>The Journal of Immunology<\/em>\u00a0204, 65.61-65.61 (2020).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0TNFR2 signaling enhances ILC2 survival, function and induction of airway hyperreactivity.\u00a0<em>The Journal of Immunology<\/em>\u00a0204, 60.65-60.65 (2020).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0Distinct roles of LFA-1 and ICAM-1 on ILC2s control lung infiltration, effector functions, and development of airway hyperreactivity.\u00a0<em>Frontiers in immunology<\/em>\u00a011, 542818 (2020).<\/li>\n<li><strong>Liu, J. et al.<\/strong>\u00a0Perinatal nicotine exposure\u2010induced transgenerational asthma: Effects of reexposure in F1 gestation.\u00a0<em>The FASEB Journal<\/em>\u00a034, 11444-11459 (2020).<\/li>\n<li><strong>Martin, M. Et Al.<\/strong>\u00a0Evidence For Pulmonary Group 2 Innate Lymphoid Type Ii Cell Involvement In Perinatal Nicotine-Induced Asthma.\u00a0<em>Journal Of Investigative Medicine<\/em>\u00a02020. P. A56-A56.<\/li>\n<li><strong>Painter, J.D., Galle-Treger, L. &amp; Akbari, O.<\/strong>\u00a0Role of autophagy in lung inflammation.\u00a0<em>Frontiers in Immunology<\/em>11, 1337 (2020).<\/li>\n<li><strong>Sattler, F.R. et al.<\/strong>\u00a0Feasibility of quantifying change in immune white cells in abdominal adipose tissue in response to an immune modulator in clinical obesity.\u00a0<em>Plos one<\/em>\u00a015, e0237496 (2020).<\/li>\n<li><strong>Shafiei-Jahani, P. et al.<\/strong>\u00a0DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus.\u00a0<em>Nature communications<\/em>\u00a011, 4718 (2020).<\/li>\n<\/ul>\n<p><strong>2019<\/strong><\/p>\n<ul>\n<li><strong>Galle, L. et al.<\/strong>\u00a0Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.\u00a0<em>The Journal of Immunology<\/em>\u00a0202, 122.110-122.110 (2019).<\/li>\n<li><strong>Galle-Treger, L. et al.<\/strong>\u00a0Autophagy is critical for type 2 innate lymphoid cell metabolic homeostasis and effector function.\u00a0<em>European Journal Of Immunology<\/em>\u00a02019: Wiley. P. 428-429.<\/li>\n<li><strong>Galle-Treger, L. et al.<\/strong>\u00a0Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.\u00a0<em>Nature communications<\/em>\u00a010, 713 (2019).<\/li>\n<li><strong>Han, Y. et al.<\/strong>\u00a0Large-scale genetic analysis identifies 66 novel loci for asthma.\u00a0<em>bioRxiv<\/em>, 749598 (2019).<\/li>\n<li><strong>Hirose, S. et al.<\/strong>\u00a0Roles of type 1, 2, and 3 innate lymphoid cells in herpes simplex virus 1 infection in vitro and in vivo.\u00a0<em>Journal of Virology<\/em>\u00a093, 10.1128\/jvi. 00523-00519 (2019).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0Modulation of ILC2 trafficking and effector functions in ILC2-driven airway hyperreactivity.\u00a0<em>The Journal of Immunology<\/em>\u00a0202, 51.12-51.12 (2019).<\/li>\n<li><strong>Hurrell, B.P. et al.<\/strong>\u00a0TNFR2 signaling enhances ILC2 survival, function, and induction of airway hyperreactivity.\u00a0<em>Cell reports<\/em>\u00a029, 4509-4524. e4505 (2019).<\/li>\n<li><strong>Kim, M.H., Akbari, O., Genyk, Y., Kohli, R. &amp; Emamaullee, J.<\/strong>\u00a0Immunologic benefit of maternal donors in pediatric living donor liver transplantation.\u00a0<em>Pediatric transplantation<\/em>\u00a023, e13560 (2019).<\/li>\n<li><strong>Lewis, G. et al.<\/strong>\u00a0Dietary fiber-induced microbial short chain fatty acids suppress ILC2-dependent airway inflammation.\u00a0<em>Frontiers in immunology<\/em>\u00a010, 2051 (2019).<\/li>\n<li><strong>Li, S. et al.<\/strong>\u00a0Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance.\u00a0<em>Nature communications<\/em>\u00a010, 1693 (2019).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity.\u00a0<em>PLoS Genetics<\/em>\u00a015, e1008528 (2019).<\/li>\n<li><strong>Quach, C. et al.<\/strong>\u00a0A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.\u00a0<em>Nature Communications<\/em>\u00a010, 5681 (2019).<\/li>\n<li><strong>Woodward, N.C. et al.<\/strong>\u00a0Exposure to nanoscale particulate matter from gestation to adulthood impairs metabolic homeostasis in mice.\u00a0<em>Scientific reports<\/em>\u00a09, 1816 (2019).<\/li>\n<\/ul>\n<p><strong>2018<\/strong><\/p>\n<ul>\n<li><strong>Biefer, H.R.C. et al.<\/strong>\u00a0Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0142, 1894-1908. e1897 (2018).<\/li>\n<li><strong>Hurrell, B.P., Shafiei Jahani, P. &amp; Akbari, O.<\/strong>\u00a0Social networking of group two innate lymphoid cells in allergy and asthma.\u00a0<em>Frontiers in immunology<\/em>\u00a09, 2694 (2018).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0Activated plasmacytoid dendritic cells regulate type 2 innate lymphoid cell\u2013mediated airway hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0141, 893-905. e896 (2018).<\/li>\n<li><strong>Ogasawara, N. et al.<\/strong>\u00a0IL-10, TGF-\u03b2, and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cells.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0141, 1147-1151. e1148 (2018).<\/li>\n<li><strong>Rao, P. et al.<\/strong>\u00a0Herpes simplex virus 1 specifically targets human CD1d antigen presentation to enhance its pathogenicity.\u00a0<em>Journal of virology<\/em>\u00a092, 10.1128\/jvi. 01490-01418 (2018).<\/li>\n<\/ul>\n<p><strong>2017<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O.<\/strong>\u00a0Maazi H., Suzuki Y., Jung J.\u00a0<em>Journal Of Allergy And Clinical Immunology<\/em>\u00a0139, 712-713 (2017).<\/li>\n<li><strong>Aron, J. &amp; Akbari, O.<\/strong>\u00a0Regulatory T cells and type 2 innate lymphoid cell\u2010dependent asthma.\u00a0<em>Allergy<\/em>\u00a072, 1148-1155 (2017).<\/li>\n<li><strong>Bensman, T.J. et al.<\/strong>\u00a0Efficacy of rhesus theta-defensin-1 in experimental models of Pseudomonas aeruginosa lung infection and inflammation.\u00a0<em>Antimicrobial Agents and Chemotherapy<\/em>\u00a061, 10.1128\/aac. 00154-00117 (2017).<\/li>\n<li><strong>Maazi, H. &amp; Akbari, O.<\/strong>\u00a0Type two innate lymphoid cells: the Janus cells in health and disease.\u00a0<em>Immunological reviews<\/em>\u00a0278, 192-206 (2017).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0Toll-like receptor-7-mediated activation of pDCs suppresses the ILC2-mediated airway hyperreactivity and inflammation through type-I interferon.\u00a0<em>The Journal of Immunology<\/em>\u00a0198, 53.57-53.57 (2017).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0Identification of the genetic determinants for the frequency of regulatory T cells using system genetics.\u00a0<em>The Journal of Immunology<\/em>\u00a0198, 220.210-220.210 (2017).<\/li>\n<li><strong>Maazi, H., Suzuki, Y., Jung, J. &amp; Akbari, O.<\/strong>\u00a0A possible differential role of autophagy in asthma?\u00a0<em>Journal Of Allergy And Clinical Immunology<\/em>\u00a0139, 712-713 (2017).<\/li>\n<li><strong>Poposki, J.A. et al.<\/strong>\u00a0Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps.\u00a0<em>Immunity, inflammation and disease<\/em>\u00a05, 233-243 (2017).<\/li>\n<li><strong>Qin, X. et al.<\/strong>\u00a0Increased innate lymphoid cells in periodontal tissue of the murine model of periodontitis: the role of AMP-activated protein kinase and relevance for the human condition.\u00a0<em>Frontiers in immunology<\/em>\u00a08, 922 (2017).<\/li>\n<li><strong>Rigas, D. et al.<\/strong>\u00a0Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator\u2013inducible T-cell costimulator ligand interaction.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0139, 1468-1477. e1462 (2017).<\/li>\n<\/ul>\n<p><strong>2016<\/strong><\/p>\n<ul>\n<li><strong>Galle-Treger, L. et al.<\/strong>\u00a0Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity.\u00a0<em>Nature communications<\/em>\u00a07, 13202 (2016).<\/li>\n<li><strong>Gyllenhammer, L.E. et al.<\/strong>\u00a0Lower omental t\u2010regulatory cell count is associated with higher fasting glucose and lower \u03b2\u2010cell function in adults with obesity.\u00a0<em>Obesity<\/em>\u00a024, 1274-1282 (2016).<\/li>\n<li><strong>Kerzerho, J. et al.<\/strong>\u00a0Impact of hepatitis C virus on the circulating levels of IL-7 in HIV-1 coinfected women.\u00a0<em>JAIDS Journal of Acquired Immune Deficiency Syndromes<\/em>\u00a071, 172-180 (2016).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0Impairment of Autophagy in Pulmonary CD11c+ Cells Induces Corticosteroid-Unresponsive Airway Hyperreactivity.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0137, AB410 (2016).<\/li>\n<li><strong>Pulido, M.A. et al.<\/strong>\u00a0Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4.\u00a0<em>Journal of neuroimmunology<\/em>\u00a0299, 70-78 (2016).<\/li>\n<li><strong>Rigas, D. et al.<\/strong>\u00a0ILC2 suppression by regulatory T cells attenuates airway hyperreactivity and requires ICOS: ICOS-ligand interaction.\u00a0<em>The Journal of allergy and clinical immunology<\/em>\u00a0139, 1468 (2016).<\/li>\n<li><strong>Simmerman, E. et al.<\/strong>\u00a0Innate lymphoid cells: a paradigm for low SSI in cleft lip repair.\u00a0<em>Journal of Surgical Research<\/em>\u00a0205, 312-317 (2016).<\/li>\n<li><strong>Suzuki, Y. et al.<\/strong>\u00a0Lack of autophagy induces steroid-resistant airway inflammation.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0137, 1382-1389. e1389 (2016).<\/li>\n<li><strong>Tian, Y., Kuo, C.-f., Akbari, O. &amp; Ou, J.-h.J.<\/strong>\u00a0Maternal-derived hepatitis B virus e antigen alters macrophage function in offspring to drive viral persistence after vertical transmission.\u00a0<em>Immunity<\/em>\u00a044, 1204-1214 (2016).<\/li>\n<li><strong>Zhang, J. et al.<\/strong>\u00a0I\u03baB kinase \u03b5 is an NFATc1 kinase that inhibits T cell immune response.\u00a0<em>Cell reports<\/em>\u00a016, 405-418 (2016).<\/li>\n<\/ul>\n<p><strong>2015<\/strong><\/p>\n<ul>\n<li><strong>Maazi, H. &amp; Akbari, O.<\/strong>\u00a0ICOS regulates ILC2s in asthma.\u00a0<em>Oncotarget<\/em>\u00a06, 24584 (2015).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0ICOS: ICOS-ligand interaction is essential for ILC2 function and survival (HYP2P. 322).\u00a0<em>The Journal of Immunology<\/em>\u00a0194, 53.53-53.53 (2015).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0ICOS: ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity.\u00a0<em>Immunity<\/em>\u00a042, 538-551 (2015).<\/li>\n<li><strong>Mott, K.R. et al.<\/strong>\u00a0Batf3 deficiency is not critical for the generation of CD8\u03b1+ dendritic cells.\u00a0<em>Immunobiology<\/em>\u00a0220, 518-524 (2015).<\/li>\n<li><strong>Suzuki, Y. Et Al.<\/strong>\u00a0Nicotinic Acetylcholine Receptor Agonist Attenuates Innate Lymphocyte Cells Type 2 Dependant Airway Hyper-Reactivity.\u00a0<em>American Thoracic Society<\/em>, 2015, Pp A5170-A5170.<\/li>\n<li><strong>Suzuki, Y. Et Al.<\/strong>\u00a0C101 Allergic Airway Inflammation And Hyperresponsiveness: Novel Mechanisms And Therapy.\u00a0<em>American Journal Of Respiratory And Critical Care Medicine<\/em>\u00a0191, 1 (2015).<\/li>\n<li><strong>Wen, X. et al.<\/strong>\u00a0A subset of CD8\u03b1\u03b2+ invariant NKT cells in a humanized mouse model.\u00a0<em>The Journal of Immunology<\/em>195, 1459-1469 (2015).<\/li>\n<\/ul>\n<p><strong>2014<\/strong><\/p>\n<ul>\n<li><strong>Gyllenhammer, L.E. Et Al.<\/strong>\u00a0T-Regulatory Cells In Omental And Not Subcutaneous Adipose Tissue Inversely Associated With Fasting Glucose In Obese Adults.\u00a0<em>Diabetes<\/em>\u00a02014. P. A75-A75.<\/li>\n<li><strong>Kerzerho, J., Szely, N., Lombardi, V., Speak, A. &amp; Akbari, O.<\/strong>\u00a0Nicotine Exposure Abrogates Respiratory Tolerance By Modulating Tolerogenic Dendritic Cells And Regulatory T Cells.\u00a0<em>Respirology<\/em>\u00a02014. P. 18-18.<\/li>\n<li><strong>Maazi, H., Lombardi, V. &amp; Akbari, O.<\/strong>\u00a0Response to \u201cCD8 subunit expression by plasmacytoid dendritic cells is variable, and does not define stable subsets\u201d.\u00a0<em>Mucosal Immunology<\/em>\u00a07, 1278-1279 (2014).<\/li>\n<li><strong>Mott, K.R. et al.<\/strong>\u00a0Inclusion of CD80 in HSV targets the recombinant virus to PD-L1 on DCs and allows productive infection and robust immune responses.\u00a0<em>PloS one<\/em>\u00a09, e87617 (2014).<\/li>\n<li><strong>Mott, K.R. et al.<\/strong>\u00a0Batf3 deficiency is not critical for the generation of CD8+ dendritic cells. (2014).<\/li>\n<li><strong>Pulido, M.A. et al.<\/strong>\u00a0Fluctuating antibody response and CD4-positive T-cells in a small-cell lung cancer mouse model.\u00a0<em>Cancer Research<\/em>\u00a074, 3623-3623 (2014).<\/li>\n<li><strong>Suzuki, Y., Maazi, H., Lam, J., Jung, J. &amp; Akbari, O.<\/strong>\u00a0Lack Of Autopgagy In Dendritic Cells Induces Steroid Resistant, Il-17 Dependent Airway Hyperreactivity.\u00a0<em>American Journal Of Respiratory And Critical Care Medicine<\/em>189, 1 (2014).<\/li>\n<li><strong>Suzuki, Y., Mazzi, H., Lam, J., Jung, J.U. &amp; Akbari, O.<\/strong>\u00a0Lack Of Autopgagy In Dendritic Cells Induces Steroid Resistant, Il-17 Dependent Airway Hyperreactivity.\u00a0<em>American Thoracic Society<\/em>, 2014, Pp A5356-A5356.<\/li>\n<\/ul>\n<p><strong>2013<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0Programmed cell death ligand 2 regulates Th9 differentiation and induction of chronic airway hyperreactivity (P6261).\u00a0<em>The Journal of Immunology<\/em>\u00a0190, 181.113-181.113 (2013).<\/li>\n<li><strong>Kerzerho, J. et al.<\/strong>\u00a0Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity.\u00a0<em>Journal of allergy and clinical immunology<\/em>\u00a0131, 1048-1057. e1042 (2013).<\/li>\n<li><strong>Liu, J. Et Al.<\/strong>\u00a0Gender-Specific Effects Of Perinatal Nicotine-Induced Asthma On Upper Vs Lower Airway Of Rat Offspring.\u00a0<em>Journal Of Investigative Medicine<\/em>\u00a02013. P. 145-145.<\/li>\n<li><strong>Liu, J. et al.<\/strong>\u00a0Sex-specific perinatal nicotine-induced asthma in rat offspring.\u00a0<em>American journal of respiratory cell and molecular biology<\/em>\u00a048, 53-62 (2013).<\/li>\n<li><strong>Maazi, H., Lam, J., Lombardi, V. &amp; Akbari, O.<\/strong>\u00a0Role of plasmacytoid dendritic cell subsets in allergic asthma.\u00a0<em>Allergy<\/em>\u00a068, 695-701 (2013).<\/li>\n<li><strong>Maazi, H. et al.<\/strong>\u00a0Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.\u00a0<em>PloS one<\/em>\u00a08, e59599 (2013).<\/li>\n<li><strong>Rofoogaran, M., Barbers, R. &amp; Akbari, O.<\/strong>\u00a0Role Of Il-25 Receptor On Inkt Cells In Human Severe Asthma.\u00a0<em>American Thoracic Society<\/em>, 2013, Pp A1256-A1256.<\/li>\n<\/ul>\n<p><strong>2012<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O.<\/strong>\u00a0Hadi Maazi, DVM, PhD Yuzo Suzuki, MD, PhD Jae Jung, PhD.\u00a0<em>Clin Immunol<\/em>\u00a0129, 569-571 (2012).<\/li>\n<li><strong>Kerzerho, J. et al.<\/strong>\u00a0Effects of systemic versus local administration of corticosteroids on mucosal tolerance.\u00a0<em>The Journal of Immunology<\/em>\u00a0188, 470-476 (2012).<\/li>\n<li><strong>Kerzerho, J. et al.<\/strong>\u00a0Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.\u00a0<em>Journal of Immunology<\/em>\u00a0189, 4194 (2012).<\/li>\n<li><strong>Kerzerho, J. et al.<\/strong>\u00a0Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.\u00a0<em>The Journal of Immunology<\/em>\u00a0188, 2254-2265 (2012).<\/li>\n<li><strong>Lombardi, V., Speak, A.O., Kerzerho, J., Szely, N. &amp; Akbari, O.<\/strong>\u00a0CD8\u03b1+ \u03b2\u2212 and CD8\u03b1+ \u03b2+ plasmacytoid dendritic cells induce Foxp3+ regulatory T cells and prevent the induction of airway hyper-reactivity.\u00a0<em>Mucosal immunology<\/em>\u00a05, 432-443 (2012).<\/li>\n<li><strong>Rehan, V.K. et al.<\/strong>\u00a0Perinatal nicotine exposure induces asthma in second generation offspring.\u00a0<em>BMC medicine<\/em>\u00a010, 129 (2012).<\/li>\n<li><strong>Tian, J. Et Al.<\/strong>\u00a0Gender-Specific Perinatal Nicotine-Induced Asthma In Rat Offspring.\u00a0<em>Journal Of Investigative Medicine<\/em>\u00a02012. P. 158-158.<\/li>\n<\/ul>\n<p><strong>2011<\/strong><\/p>\n<ul>\n<li><strong>Babu, J., Lombardi, V., Akbari, O. &amp; Barbers, R.<\/strong>\u00a0Expression of IL-25 Receptors on iNKT Cells From Patients With Severe Asthma.\u00a0<em>Chest<\/em>\u00a0140, 228A (2011).<\/li>\n<li><strong>Li, M. et al.<\/strong>\u00a0Epithelium-specific deletion of TGF-\u03b2 receptor type II protects mice from bleomycin-induced pulmonary fibrosis.\u00a0<em>The Journal of clinical investigation<\/em>\u00a0121, 277-287 (2011).<\/li>\n<li><strong>Lombardi, V., Szely, N. &amp; Akbari, O.<\/strong>\u00a0Co-expression of CD8\u03b1 and CD8\u03b2 defines a subset of tolerogenic plasmacytoid dendritic cells able to induce the differentiation of Foxp3+ regulatory T cells.\u00a0<em>The Journal of Immunology<\/em>\u00a0186, 103.109-103.109 (2011).<\/li>\n<li><strong>Singh, A.K., Stock, P. &amp; Akbari, O.<\/strong>\u00a0Role of PD\u2010L1 and PD\u2010L2 in allergic diseases and asthma.\u00a0<em>Allergy<\/em>\u00a066, 155-162 (2011).<\/li>\n<\/ul>\n<p><strong>2010<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions.\u00a0<em>Mucosal immunology<\/em>\u00a03, 81-91 (2010).<\/li>\n<li><strong>Albacker, L.A. et al.<\/strong>\u00a0TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells.\u00a0<em>The Journal of Immunology<\/em>\u00a0185, 6839-6849 (2010).<\/li>\n<li><strong>Lombardi, V., Singh, A.K. &amp; Akbari, O.<\/strong>\u00a0The role of costimulatory molecules in allergic disease and asthma.\u00a0<em>International archives of allergy and immunology<\/em>\u00a0151, 179-189 (2010).<\/li>\n<li><strong>Lombardi, V. et al.<\/strong>\u00a0A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.\u00a0<em>The journal of immunology<\/em>\u00a0184, 2107-2115 (2010).<\/li>\n<\/ul>\n<p><strong>2009<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O., Stock, P., Lombardi, V. <\/strong>Induction of Airway Hyperreactivity by IL-25.\u00a0<em>J Immunol<\/em>182, 5116-5122 (2009).<\/li>\n<li><strong>Albacker, L. et al.<\/strong>\u00a0TIM-4 Negatively Regulates Immune Responses by Reducing Antigen Specific T Cell Numbers.\u00a0<em>Clinical Immunology<\/em>\u00a0131, S36-S36 (2009).<\/li>\n<li><strong>Lombardi, V. &amp; Akbari, O.<\/strong>\u00a0Dendritic cell modulation as a new interventional approach for the treatment of asthma.\u00a0<em>Drug news &amp; perspectives<\/em>\u00a022, 445 (2009).<\/li>\n<li><strong>Matangkasombut, P. et al.<\/strong>\u00a0Natural killer T cells in the lungs of patients with asthma.\u00a0<em>Journal of allergy and clinical immunology<\/em>\u00a0123, 1181-1185. e1181 (2009).<\/li>\n<li><strong>Stock, P., Lombardi, V., Kohlrautz, V. &amp; Akbari, O.<\/strong>\u00a0Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB.\u00a0<em>The Journal of Immunology<\/em>\u00a0182, 5116-5122 (2009).<\/li>\n<\/ul>\n<p><strong>2008<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0ICOS\/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.\u00a0<em>The Journal of Immunology<\/em>\u00a0180, 5448-5456 (2008).<\/li>\n<li><strong>Exley, M.A. et al.<\/strong>\u00a0Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR \u03b1\u2010chain CDR3 loop.\u00a0<em>European journal of immunology<\/em>\u00a038, 1756-1766 (2008).<\/li>\n<li><strong>Koh, Y.I. et al.<\/strong>\u00a0Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in \u03b22-microglobulin-deficient mice.\u00a0<em>The Journal of Immunology<\/em>\u00a0181, 4560-4569 (2008).<\/li>\n<li><strong>Stock, P. &amp; Akbari, O.<\/strong>\u00a0Recent advances in the role of NKT cells in allergic diseases and asthma.\u00a0<em>Current Allergy and Asthma Reports<\/em>\u00a08, 165-170 (2008).<\/li>\n<\/ul>\n<p><strong>2007<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O.<\/strong>\u00a0PS2-2 The role of iNKT cells in development and pathogenesis of allergic disease and asthma.\u00a0<em>Japanese Journal of Allergology<\/em>\u00a056, 939 (2007).<\/li>\n<li><strong>Akbari, O., Faul, J.L. &amp; Umetsu, D.T.<\/strong>\u00a0Invariant natural killer T cells in obstructive pulmonary diseases.\u00a0<em>The New England journal of medicine<\/em>\u00a0357, 193-194 (2007).<\/li>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0ICOS\/ICOSL interaction is required for CD4+ NKT cells function and for the induction of airway hyperreactivity (39.4).\u00a0<em>The Journal of Immunology<\/em>\u00a0178, S25-S25 (2007).<\/li>\n<li><strong>Akbari, O., Yang, W., Meyer, E., Umetsu, D.T. &amp; Wilson, S.B.<\/strong>\u00a0A CD1d-dependent antagonist inhibits the activation of iNKT cells and prevents development of allergen-induced airway hyperreactivity (39.9).\u00a0<em>The Journal of Immunology<\/em>\u00a0178, S27-S27 (2007).<\/li>\n<li><strong>Stock, P. et al.<\/strong>\u00a0Induction of T (H) 1-like regulatory cells that express Foxp3 and protect against airway hyperreactivity.\u00a0<em>European Journal Of Pediatrics<\/em>\u00a02007: Springer. P. 287-288.<\/li>\n<\/ul>\n<p><strong>2006<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O.<\/strong>\u00a0The role of iNKT cells in development of bronchial asthma: a translational approach from animal models to human.\u00a0<em>Allergy<\/em>\u00a061, 962-968 (2006).<\/li>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0CD4+ invariant T-cell\u2013receptor+ natural killer T cells in bronchial asthma.\u00a0<em>New England Journal of Medicine<\/em>\u00a0354, 1117-1129 (2006).<\/li>\n<li><strong>Akbari, O., Faul, J.L. &amp; Umetsu, D.T.<\/strong>\u00a0Invariant Natural Killer T Cells in Bronchial Asthma.\u00a0<em>New England Journal of Medicine<\/em>\u00a0354, 2615-2616 (2006).<\/li>\n<li><strong>Akbari, O. &amp; Umetsu, D.T.<\/strong>\u00a0Reply to Natural killer T cells and CD8+ T cells are dispensable for T cell\u2013dependent allergic airway inflammation.\u00a0<em>Nature Medicine<\/em>\u00a012, 1347-1347 (2006).<\/li>\n<li><strong>Akbari, O. &amp; Umetsu, D.T.<\/strong>\u00a0Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation.\u00a0<em>Nature medicine<\/em>\u00a012, 1345-1347 (2006).<\/li>\n<li><strong>Meyer, E.H. et al.<\/strong>\u00a0Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells.\u00a0<em>Proceedings of the National Academy of Sciences<\/em>\u00a0103, 2782-2787 (2006).<\/li>\n<\/ul>\n<p><strong>2005<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0CD4 (+) invariant T cell receptor (+) NKT cells and the development of bronchial asthma in humans.\u00a0<em>Clinical Immunology<\/em>\u00a02005. P. S16-S17.<\/li>\n<li><strong>Akbari, O. &amp; Umetsu, D.T.<\/strong>\u00a0Role of regulatory dendritic cells in allergy and asthma.\u00a0<em>Current allergy and asthma reports<\/em>\u00a05, 56-61 (2005).<\/li>\n<li><strong>Meyer, E. et al.<\/strong>\u00a0Glycolipid mediated activation of iNKT cells is sufficient to induce airway hyperreactivity independent of conventional CD4 T cells.\u00a0<em>Clinical Immunology<\/em>\u00a02005. P. S14-S15.<\/li>\n<li><strong>Stock, P., Akbari, O., DeKruyff, R.H. &amp; Umetsu, D.T.<\/strong>\u00a0Respiratory tolerance is inhibited by the administration of corticosteroids.\u00a0<em>The Journal of Immunology<\/em>\u00a0175, 7380-7387 (2005).<\/li>\n<li><strong>Stock, P., Akbari, O., Freeman, G., DeKruyff, R. &amp; Umetsu, D.<\/strong>\u00a0Induction of THI-like regulatory cells that express Foxp3 and protect against airway hyperreactivity.\u00a0<em>Clinical Immunology<\/em>\u00a02005. P. S11-S11.<\/li>\n<li><strong>Umetsu, D.T. et al.<\/strong>\u00a0NKT cells regulate the development of asthma.\u00a0<em>International Congress Series<\/em>\u00a02005: Elsevier. p. 184-188.<\/li>\n<li><strong>Umetsu, S. et al.<\/strong>\u00a0Costimulation by TIM-1 induces T cell activation and inhibits the development of peripheral tolerance.\u00a0<em>Faseb Journal<\/em>\u00a02005. P. A905-A905.<\/li>\n<li><strong>Umetsu, S.E. et al.<\/strong>\u00a0TIM-1 induces T cell activation and inhibits the development of peripheral tolerance.\u00a0<em>Nature immunology<\/em>\u00a06, 447-454 (2005).<\/li>\n<\/ul>\n<p><strong>2004<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. &amp; Umetsu, D.T.<\/strong>\u00a0Role of regulatory dendritic cells in allergy and asthma.\u00a0<em>Current Opinion in Allergy and Clinical Immunology<\/em>\u00a04, 533-538 (2004).<\/li>\n<li><strong>Stock, P. et al.<\/strong>\u00a0Induction of T helper type 1\u2013like regulatory cells that express Foxp3 and protect against airway hyper-reactivity.\u00a0<em>Nature immunology<\/em>\u00a05, 1149-1156 (2004).<\/li>\n<li><strong>Stock, P. et al.<\/strong>\u00a0CD8+ T cells regulate immune responses in a murine model of allergen\u2010induced sensitization and airway inflammation.\u00a0<em>European journal of immunology<\/em>\u00a034, 1817-1827 (2004).<\/li>\n<\/ul>\n<p><strong>2003<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O., Freeman, G. &amp; Meyer, E.<\/strong>\u00a0Primary immune deficiency.\u00a0<em>Cardiovasc Res<\/em>\u00a059, 95-104 (2003).<\/li>\n<li><strong>Akbari, O., Stock, P., DeKruyff, R.H. &amp; Umetsu, D.T.<\/strong>\u00a0Role of regulatory T cells in allergy and asthma.\u00a0<em>Current opinion in immunology<\/em>\u00a015, 627-633 (2003).<\/li>\n<li><strong>Akbari, O., Stock, P., DeKruyff, R.H. &amp; Umetsu, D.T.<\/strong>\u00a0Mucosal tolerance and immunity: regulating the development of allergic disease and asthma.\u00a0<em>International archives of allergy and immunology<\/em>\u00a0130, 108-118 (2003).<\/li>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity.\u00a0<em>Nature medicine<\/em>\u00a09, 582-588 (2003).<\/li>\n<li><strong>Umetsu, D.T., Akbari, O. &amp; DeKruyff, R.H.<\/strong>\u00a0Regulatory T cells control the development of allergic disease and asthma.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0112, 480-487 (2003).<\/li>\n<li><strong>Umetsu, D.T. et al.<\/strong>\u00a0Regulatory T cells control the development of allergic disease and asthma.\u00a0<em>Journal of Allergy and Clinical Immunology<\/em>\u00a0112, 480-487 (2003).<\/li>\n<\/ul>\n<p><strong>2002<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0Antigen-specific regulatory T cells develop via the ICOS\u2013ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity.\u00a0<em>Nature medicine<\/em>\u00a08, 1024-1032 (2002).<\/li>\n<li><strong>Oh, J.-W. et al.<\/strong>\u00a0CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation.\u00a0<em>Journal of allergy and clinical immunology<\/em>\u00a0110, 460-468 (2002).<\/li>\n<li><strong>Umetsu, D. et al.<\/strong>\u00a0Nature Review.\u00a0<em>Nature Immunology<\/em>\u00a0(2002).<\/li>\n<li><strong>Umetsu, D.T., McIntire, J.J., Akbari, O., Macaubas, C. &amp; DeKruyff, R.H.<\/strong>\u00a0Asthma: an epidemic of dysregulated immunity.\u00a0<em>Nature immunology<\/em>\u00a03, 715-720 (2002).<\/li>\n<\/ul>\n<p><strong>2001<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O., DeKruyff, R.H. &amp; Umetsu, D.T.<\/strong>\u00a0Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen.\u00a0<em>Nature immunology<\/em>\u00a02, 725-731 (2001).<\/li>\n<li><strong>McIntire, J.J. et al.<\/strong>\u00a0Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.\u00a0<em>Nature immunology<\/em>\u00a02, 1109-1116 (2001).<\/li>\n<\/ul>\n<p><strong>1999<\/strong><\/p>\n<ul>\n<li><strong>Akbari, O.<\/strong>\u00a0Analysis of the basis for induction and maintenance of T cell responses in DNA vaccination.\u00a0<em>University College London<\/em>, 1999.<\/li>\n<li><strong>Akbari, O. et al.<\/strong>\u00a0DNA vaccination: transfection and activation of dendritic cells as key events for immunity.\u00a0<em>The Journal of experimental medicine<\/em>\u00a0189, 169-178 (1999).<\/li>\n<li><strong>Panjwani, N., Akbari, O., Garcia, S., Brazil, M. &amp; Stockinger, B.<\/strong>\u00a0The HSC73 molecular chaperone: involvement in MHC class II antigen presentation.\u00a0<em>The Journal of Immunology<\/em>\u00a0163, 1936-1942 (1999).<\/li>\n<\/ul>\n<h6 align=\"justify\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/omid.akbari.1\/bibliography\/public\/\">Please click here to view listing of our <\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/omid.akbari.1\/bibliography\/public\/\">publications on PubMed<\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/omid.akbari.1\/bibliography\/public\/\">.\u00a0<\/a><\/h6>\n","protected":false},"excerpt":{"rendered":"<p>2025 Barbetta, A. et al.\u00a0Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite.\u00a0Scientific Reports\u00a015, 9394 (2025). Cain, J., Hurrell, B. &amp; Akbari, O.\u00a0The Expanding Role of ILC2s in Allergic Airways Disease.\u00a0Allergy(2025). Chandan, G. et al.\u00a0Perinatal Flavored E-cigarette Exposure and the Critical Role of Innate Lymphoid type II Cells in Transgenerational Asthma Transmission.\u00a0Journal [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/pages\/21"}],"collection":[{"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21"}],"version-history":[{"count":49,"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/pages\/21\/revisions"}],"predecessor-version":[{"id":977,"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=\/wp\/v2\/pages\/21\/revisions\/977"}],"wp:attachment":[{"href":"http:\/\/uscmmi.com\/omidakbarilab\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}