Viral Pseudo-Enzymes Activate RIG-I via Deamidation to Evade Cytokine Production.

He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung JU, Zhang X, Feng P.

Mol Cell. 2015 Mar 4. pii: S1097-2765(15)00059-3. doi: 10.1016/j.molcel.2015.01.036. [Epub ahead of print]

PMID: 25752576


Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression.

Patel N, Itakura T, Jeong S, Liao CP, Roy-Burman P, Zandi E, Groshen S, Pinski J, Coetzee GA, Gross ME, Fini ME.

PLoS One. 2015 Feb 18;10(2):e0117758. doi: 10.1371/journal.pone.0117758. eCollection 2015.

PMID: 25693195 Free PMC Article


Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice.

Yang H, Li TW, Zhou Y, Peng H, Liu T, Zandi E, Martínez-Chantar ML, Mato JM, Lu SC.

Antioxid Redox Signal. 2015 Jan 20;22(3):259-74. doi: 10.1089/ars.2014.6027. Epub 2014 Oct 17.

PMID: 25226451


Hydrogen sulfide maintains mesenchymal stem cell function and bone homeostasis via regulation of Ca(2+) channel sulfhydration.

Liu Y, Yang R, Liu X, Zhou Y, Qu C, Kikuiri T, Wang S, Zandi E, Du J, Ambudkar IS, Shi S.

Cell Stem Cell. 2014 Jul 3;15(1):66-78. doi: 10.1016/j.stem.2014.03.005. Epub 2014 Apr 10.

PMID: 24726192


CAF-secreted annexin A1 induces prostate cancer cells to gain stem cell-like features.

Geary LA, Nash KA, Adisetiyo H, Liang M, Liao CP, Jeong JH, Zandi E, Roy-Burman P.

Mol Cancer Res. 2014 Apr;12(4):607-21. doi: 10.1158/1541-7786.MCR-13-0469. Epub 2014 Jan 24.

PMID: 24464914


Novel Phosphorylations of IKKγ/NEMO.

Lee SH, Toth Z, Wong LY, Brulois K, Nguyen J, Lee JY, Zandi E, Jung JU.

MBio. 2012 Nov 6;3(6):e00411-12. doi: 10.1128/mBio.00411-12.

PMID: 23131831 Free PMC Article


Site-specific modification of adeno-associated viruses via a genetically engineered aldehyde tag.

Liu Y, Fang Y, Zhou Y, Zandi E, Lee CL, Joo KI, Wang P.

Small. 2013 Feb 11;9(3):421-9. doi: 10.1002/smll.201201661. Epub 2012 Oct 5.

PMID: 23038676


Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.

Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16348-53. doi: 10.1073/pnas.1205226109. Epub 2012 Sep 17.

PMID: 22988091 Free PMC Article


Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):264-76. doi: 10.1016/j.chom.2012.01.018.

PMID: 22423966 Free PMC Article


Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs).

Yamada R, Cao X, Butkevich AN, Millard M, Odde S, Mordwinkin N, Gundla R, Zandi E, Louie SG, Petasis NA, Neamati N.

J Med Chem. 2011 Apr 28;54(8):2902-14. doi: 10.1021/jm101655d. Epub 2011 Mar 28.

PMID: 21443194


Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1.

Higashimoto T, Chan N, Lee YK, Zandi E.

J Biol Chem. 2008 Dec 19;283(51):35354-67. doi: 10.1074/jbc.M806258200. Epub 2008 Oct 27.

PMID: 18957422 Free PMC Article


A simple and inexpensive on-column frit fabrication method for fused-silica capillaries for increased capacity and versatility in LC-MS/MS applications.

Wang LC, Okitsu CY, Kochounian H, Rodriguez A, Hsieh CL, Zandi E.

Proteomics. 2008 May;8(9):1758-61. doi: 10.1002/pmic.200700931.

PMID: 18384106


TNFalpha induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways.

Higashimoto T, Panopoulos A, Hsieh CL, Zandi E.

Cytokine. 2006 Apr;34(1-2):39-50. Epub 2006 May 24.

PMID: 16723255


Regulation of IkappaB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKbeta.

Schomer-Miller B, Higashimoto T, Lee YK, Zandi E.

J Biol Chem. 2006 Jun 2;281(22):15268-76. Epub 2006 Apr 5.

PMID: 16597623 Free Article


Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.

Wang LC, Okitsu CY, Zandi E.

J Biol Chem. 2005 Mar 4;280(9):7634-44. Epub 2004 Dec 17.

PMID: 15611081 Free Article